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Case Studies > Optimizing Cell Engineering with a Unified Informatics Platform

Optimizing Cell Engineering with a Unified Informatics Platform

Technology Category
  • Platform as a Service (PaaS) - Data Management Platforms
Applicable Industries
  • Healthcare & Hospitals
  • Life Sciences
Applicable Functions
  • Product Research & Development
  • Quality Assurance
Use Cases
  • Predictive Quality Analytics
  • Root Cause Analysis & Diagnosis
Services
  • Software Design & Engineering Services
  • System Integration
The Challenge
Rubius Therapeutics faced several challenges in their cell engineering processes. Their manual record-keeping systems were disorganized and cluttered, making it difficult for teams to collaborate effectively. The company's legacy request management protocols were inefficient, requiring scientists and managers to sift through scattered records on cell cultures and quality control assays. Furthermore, their engineering processes were out of sync and hard to track due to decentralized information storage systems and unreliable reporting on project progress.
About The Customer
Rubius Therapeutics is a biotechnology company that genetically engineers red blood cell therapeutics, or RCTs, to treat a variety of diseases. These RCTs have the potential to target cancer by activating immunity, treat autoimmune diseases through self-antigen tolerance induction, and combat rare enzyme deficiencies by introducing therapeutic enzymes that are cellularly shielded. The company is at the forefront of cell engineering, but their processes were hindered by inefficient systems and protocols.
The Solution
Rubius Therapeutics implemented Benchling's unified informatics platform to optimize their cell engineering processes. The platform allowed Rubius to store, share, and interlink all their experimental data, improving cross-team collaboration. Benchling's request management system streamlined Rubius's request fulfillment process, enabling them to track experiment status and forecast needs in real-time. Additionally, Benchling Workflows helped Rubius structure, execute, and optimize their cell engineering processes, from DNA production to cell construction. The platform also facilitated seamless filing and tracking of requests, and provided real-time visibility into laboratory needs and resources.
Operational Impact
  • Improved cross-team collaboration through the interlinking of all experimental data.
  • Streamlined request fulfillment process, enabling real-time tracking of experiment status and forecasting of needs.
  • Structured and optimized cell engineering processes through Benchling Workflows.

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