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Case Studies > Enabling Next-Generation Cell Therapies with a Scalable Informatics Solution

Enabling Next-Generation Cell Therapies with a Scalable Informatics Solution

Technology Category
  • Platform as a Service (PaaS) - Data Management Platforms
Applicable Industries
  • Healthcare & Hospitals
  • Life Sciences
Applicable Functions
  • Product Research & Development
Services
  • Data Science Services
The Challenge
Adicet Bio, a company that employs gamma delta T-cells to target solid tumor cancer, faced several challenges in managing their data. Their data was scattered across paper notebooks, employee computers, and public drives, making it difficult to access and secure. Their previous data management platform struggled to provide varying levels of access permissions to data for the stratified teams across their various sites. As Adicet rapidly scaled their staff size and the complexity of their research and development process, they needed to be able to organize and standardize their data capture and record keeping.
About The Customer
Adicet Bio is a company that is broadening the horizons of cell immunotherapy with gamma delta (γδ) T-cells. They employ these cells’ unique properties to target solid tumor cancer. Though gamma delta T-cells make up a small fraction of blood cells, Adicet has developed a platform to activate and expand these cells for function in the clinic. Adicet Bio has fully functional sites in California and Israel. These two sites operate both independently and in conjunction, and Benchling has helped them establish unique permissions structures respective to the sites’ needs.
The Solution
Adicet Bio adopted Benchling, a comprehensive data management platform. With Benchling, all of Adicet’s data types are unified on a cohesive data layer. Entities and results are connected to context-rich Notebook entries via bio-intelligent links. Benchling allows Adicet to have tiered access permissions: read-only, append and write, and administrate. They can now specify access level to data, projects, within Benchling’s applications. With Benchling, Adicet now has an organizational infrastructure that standardizes their project folder structure and data entry to document experimental history.
Operational Impact
  • Adicet Bio has secured its data’s integrity by storing, centralizing, and compiling it within Benchling. This comprehensive data management prepares Adicet to efficiently file for IND.
  • With Benchling’s data access features, Adicet can flexibly turn data and folder permissions on and off, depending on teams’ needs.
  • Adicet standardizes data entry and organizes data with configurable templates and entry guidelines for Notebook and Registry. These best practices provide structure as the Adicet team scales.

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